Drug Category: B

Generic Name: Bupropion Common Brand Names: Wellbutrin, Zyban, Aplenzin Introduction Bupropion is an atypical antidepressant and smoking cessation aid. It is used to treat major depressive disorder (MDD), seasonal affective disorder (SAD), and as a smoking cessation aid. It is also used off-label for weight loss and to help manage attention-deficit hyperactivity disorder (ADHD). Conditions of Use (Indications) Major Depressive Disorder (MDD): Used as a first-line treatment for patients with depression. Smoking Cessation: Sold under the brand name Zyban for smoking cessation. Seasonal Affective Disorder (SAD): An option for treating seasonal depression. Off-Label Uses: Weight loss, ADHD, and anxiety disorders. Mechanism of Action Bupropion works by inhibiting the reuptake of

Generic Name: Baclofen Common Brand Names: Lioresal, Gablofen, Kemstro Introduction Baclofen is a muscle relaxant used to treat spasticity and muscle pain associated with conditions like multiple sclerosis, spinal cord injury, and cerebral palsy. It is also sometimes used for the management of alcohol use disorder. Conditions of Use (Indications) Muscle Spasticity: Relieves muscle spasticity from neurological conditions such as multiple sclerosis and spinal cord injuries. Alcohol Use Disorder: Occasionally used to reduce cravings in patients with alcohol dependence. Cerebral Palsy: Can be used to manage spasticity in children with cerebral palsy. Mechanism of Action Baclofen acts as a gamma-aminobutyric acid (GABA) B receptor agonist in the central nervous system.