Janssen Cilag (Brand)
Generic Name: Dapagliflozin Common Brand Names: Farxiga, Forxiga Introduction Dapagliflozin is an SGLT2 inhibitor used primarily to treat type 2 diabetes, heart failure, and chronic kidney disease. It works by inhibiting the sodium-glucose co-transporter 2 (SGLT2) in the kidneys, leading to reduced glucose reabsorption and increased glucose excretion in urine. Conditions of Use (Indications) Type 2 Diabetes Mellitus: Helps to control blood glucose levels in patients with type 2 diabetes. Heart Failure: Reduces hospitalization rates and improves outcomes in patients with heart failure with reduced ejection fraction (HFrEF). Chronic Kidney Disease: Used in patients with chronic kidney disease to reduce the progression of kidney failure. Mechanism of Action Dapagliflozin inhibits